Three Bay Area students’ projects will be among those featured in the White House Science Fair on Monday in Washington, D.C.
Holly Jackson, 14, of San Jose, investigated the art of sewing from a unique, architectural point of view. After learning to sew in the 4th grade from her grandmother, Holly’s scientific curiosity led her to explore the relative strength and compatibility of threads and fabrics, important information to better understand innovative sewn materials for the 21st century. She engineered a device to measure the capacity and strength of stitched fabric, and designed experiments and procedures to yield precise measurements. Her research has potential applications in the design of high-performance protective gear, hazmat and space suits, parachutes, and more. Her work won the top award of $25,000 at the 2014 Broadcom MASTERS competition.
Natalie Ng, 19, of Cupertino, developed two micro-RNA-based prognostic models that can predict metastasis in breast cancer, and identified two micro-RNAs that independently impact the ability of breast cancer cells to metastasize. Ng’s project has important implications for breast cancer diagnosis and treatment. Breast cancer is the most prevalent cancer diagnosed in women worldwide, according to the latest WHO report. A frustrating reality about cancer is that even when initial hormonal treatment seems to work, metastatic cancer cells can survive and spread to distant sites in the body. So, accurate prediction of metastatic outcome, such as with the aid of genetic signatures, can significantly improve the ability to predict the recurrence risk and to devise appropriate treatment strategies for individual cancer patients. Ng won First Place at the 2013 International BioGENEius Challenge.
Ruchi Pandya, 18, of San Jose, combining nanotechnology, biology and electrochemistry to use small biological samples – only a single drop of blood – to test for specific cardiac biomarkers. She developed a one-square centimeter carbon nanofiber electrode-based biosensor that has the potential to improve cardiac health diagnostics for patients around the world. Ruchi takes her passion for STEM education beyond the lab by mentoring 9th and 10th grade students on research and engineering as a teaching assistant for her school’s STEM-research class. She has competed at the California State Science Fair every year, and has won 18 category and special awards for scientific research. After graduation, Ruchi intends to major in materials science and engineering, and hopes to pursue a career as a technology entrepreneur.